Little Audrey began life in the Famous Paramount animated cartoons. Her first cartoon was "Santa's Surprise" in 1947, and eventually she appeared in 16 animated shorts.
Little Audrey apparently was popular enough that soon she appeared on a number of products, had her own newspaper comic strip, and starred in her own comic book published by St. John. St. John published 24 issues of Little Audrey from 1948-1952, before she moved to Harvey.
Example of Little Audrey daily by Larry Silverman, October 19, 1951. Art size: 22" x 6 1/2".
Also, check out the gallery page for the Little Audrey comic book to see nice examples of original art for the comic.
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